Ref ID:	28614
Ref Type:	Journal Article
Authors:	Ke, Yuehai Su, Bing Song, Xiufeng Lu, Daru Chen, Lifeng Li, Hongyu Qi, Chunjian Marzuki, Songkot Deka, Ranjan Underhill, Peter Xiao, Chunjie Shriver, Mark Lell, Jeff Wallace, Douglas Wells, R. Spencer Seielstad, Mark Oefner, Peter
Title:	African origin of modern chromosomes in East Asia: a tale of 12,000 Y chromosomes
Date:	2001
Source:	Science
DOI:	10.1126/science.1060011
Notes:	Additional authors: Zhu, Dingliang Jin, Jianzhong Huang, Wei Chakraborty, Ranajit Chen, Zhu Jin, Li
Abstract:	To test the hypotheses of modern human origin in East Asia, we sampled 12,127 male individuals from 163 populations and typed for three Y chromosome biallelic markers (YAP, M89, and M130). All the individuals carried a mutation at one of the three sites. These three mutations (YAP+, M89T, and M130T) coalesce to another mutation (M168T), which originated in Africa about 35,000 to 89,000 years ago. Therefore, the data do not support even a minimal in situ hominid contribution in the origin of anatomically modern humans in East Asia.
Date Created:	10/6/2011
Volume:	292
Number:	5519
Page Start:	1151
Page End:	1153