Ref ID:	26751
Ref Type:	Journal Article
Authors:	Wang, Ling-Xiang Lu, Yan Zhang, Chao Wei, Lan-Hai Yan, Shi Huang, Yun-Zhi Wang, Chuan-Chao Mallick, Swapan Wen, Shao-Qing Jin, Li Xu, Shu-Hua Li, Hui
Title:	Reconstruction of Y-chromosome phylogeny reveals two neolithic expansions of Tibeto-Burman populations
Date:	2018
Source:	Molecular Genetics and Genomics
DOI:	10.1007/s00438-018-1461-2
Abstract:	Diffusion of Tibeto-Burman populations across the Tibetan Plateau led to the largest human community in a high-altitude environment and has long been a focus of research on high-altitude adaptation, archeology, genetics, and linguistics. However, much uncertainty remains regarding the origin, diversification, and expansion of Tibeto-Burman populations. In this study, we analyzed a 7.0M BP region of 285 Y-chromosome sequences, including 81 newly reported ones, from male samples from Tibeto-Burman populations and other related Eastern Asian populations. We identified several paternal lineages specific to Tibeto-Burman populations, and most of these lineages emerged between 6000 and 2500 years ago. A phylogenetic tree and lineage dating both support the hypothesis that the establishment of Tibeto-Burman ancestral groups was triggered by Neolithic expansions from the middle Yellow River Basin and admixtures with local populations on the Tibetan Plateau who survived the Paleolithic Age. Furthermore, according to the geographical distributions of the haplogroups, we propose that there are two Neolithic expansion origins for all modern Tibeto-Burman populations. Our research provides a clear scenario about the sources, admixture process and later diffusion process of the ancestor population of all Tibeto-Burman populations.
Date Created:	9/10/2018
Volume:	293
Number:	5
Page Start:	1293
Page End:	1300