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Ref ID: 30246
Ref Type: Journal Article
Authors: Thurnham, D. I.
Migasena, P.
Vudhivai, Niyomsri
Supawan, Venus
Title: Riboflavin supplementation in a resettlement village in north-east Thailand
Date: 1972
Source: British Journal of Nutrition
Notes: A high prevalence of biochemical ariboflavinosis was shown to be present in the preschool children and a small group of adults in a village in north-east Thailand using an in vitro test based on erythrocyte glutathione reductase (EGR) activity. A riboflavin supplement of 10 mg/d was given to all subjects for 7 d. It was demonstrated that the riboflavin supplement cured the biochemical ariboflavinosis and the results supported the previous suggestion that a stimulation 20% of the in vitro EGR activity was a good indicator of ariboflavinosis. A dietary survey carried out on twenty preschool children during the experimental period showed riboflavin intake to be low, 0.18 ± 0.06 mg/Mcal. No glucose-6-phosphate dehydrogenase (G-6-PD)-deficient subjects were shown to be deficient in riboflavin by the in vitro test. The possibillity of using in vivo stimulation of EGR activity by riboflavin is discussed as a possible way of demonstrating ariboflavinosis in G-6-PD-deficient subjects.
Date Created: 4/17/2006
Volume: 28
Number: 1
Page Start: 91
Page End: 97